hh (-)-Cytisine (CAS 485-35-8): R&D Systems
Catalog Number: 1390
Chemical Name: (1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
Biological Activity
A potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors.
Technical Data
  • M.Wt:
    190.24
  • Formula:
    C11H14N2O
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99%
  • Storage:
    Desiccate at RT
  • CAS No:
    485-35-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Localization of nicotinic cholinergic receptors in rat brain: autoradiographic studies with [3H]cytisine.
    Happe et al.
    Neuroscience, 1994;62:929
  2. Behavioural and pharmacokinetic studies on nicotine, cytisine and lobeline.
    Reavill et al.
    Neuropharmacology, 1990;29:619
  3. Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit.
    Papke et al.
    Mol.Pharmacol., 1994;45:142
Citations:

The citations listed below are publications that use Tocris products. Selected citations for (-)-Cytisine include:

1 Citations: Showing 1 - 1

  1. Cytisine induces autonomic cardiovascular responses via activations of different nicotinic receptors.
    Authors: Li Et al.
    Auton Neurosci 2010;154:14

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