Chemical Name: (1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
Biological Activity(-)-Cytisine is a potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Localization of nicotinic cholinergic receptors in rat brain: autoradiographic studies with [3H]cytisine.
Happe et al.
Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit.
Papke et al.
Behavioural and pharmacokinetic studies on nicotine, cytisine and lobeline.
Reavill et al.
Citations for (-)-Cytisine
The citations listed below are publications that use Tocris products. Selected citations for (-)-Cytisine include:
2 Citations: Showing 1 - 2
Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes.
Authors: David Et al.
Eur J Neurosci 2010;31:978
Cytisine induces autonomic cardiovascular responses via activations of different nicotinic receptors.
Authors: Li Et al.
Auton Neurosci 2010;154:14
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