Novel inhibitor of tubulin polymerization; cytotoxic and inhibits tumor cell proliferation in vitro
= 74 nM). Prevents growth of tumor models in mice following oral administration in vivo
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2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors.
Beckers et al.
Cancer Res., 2002;62:3113
Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents.
Mahboobi et al.