D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt

Tocris Bioscience | Catalog # 1420

Potent inhibitor of Ins(1,4,5)P3 5-phosphatase. Metabolite of Cat. No. 1482
Tocris Bioscience
Discontinued Product
1420 has been discontinued. View all Inositol Phosphatase Inhibitors products.

Key Product Details

Description

Potent inhibitor of Ins(1,4,5)P3 5-phosphatase. Metabolite of Cat. No. 1482
View all Inositol Phosphatase Inhibitors »

Product Description

D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt is a phosphorylation product of inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Potent inhibitor of Ins (1,4,5)P3 5-phosphatase (IC50 ~150 nM); facilitates Ca2+ influx by sensitizing Ins (1,4,5)P3-mediated activation of ICRAC. At higher concentrations, acts as an inhibitor of Ins (1,4,5)P3 receptors.

Product Specifications

Molecular Weight

804.73

Formula

C6H8O18P4.K8

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

CAS Number

145843-69-2

PubChem ID

16760517

InChI Key

HDLWTQSZUMYYND-QAVKKEKOSA-F

SMILES

[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+].O[C@H]1[C@@H](OP([O-])([O-])=O)[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]1OP([O-])([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents

Certificate of Analysis

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Product Specific Notices

For research use only

Related Research Areas

Phosphatases and Regulators

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