Chemical Name: 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one
Biological ActivityDiazepam is a ligand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Pharmacology of benzodiazepine receptors: an update.
Sieghart et al.
Citations for Diazepam
The citations listed below are publications that use Tocris products. Selected citations for Diazepam include:
8 Citations: Showing 1 - 8
Structure of a human synaptic GABAA receptor.
Local GABAA receptor mediated suppression of DA release within the nucleus accumbens.
Authors: Brodnik Et al.
ACS Chem Neurosci 2018;17:1978
Lateral diffusion of Gαs in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains.
Authors: Czysz Et al.
PLoS One 2015;40:766
In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383.
Authors: Ufuk Et al.
Pharm Res 2015;32:3937
Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT?A and 5-HT? Antagonists in Animal Models.
Authors: Pytka Et al.
PLoS One 2015;10:e0142499
Membrane potential measurements of isolated neurons using a voltage-sensitive dye.
Authors: Fairless Et al.
PLoS One 2013;8:e58260
A translational rodent assay of affective biases in depression and antidepressant therapy.
Authors: Stuart Et al.
A refractory period for rejuvenating GABAergic synaptic transmission and ocular dominance plasticity with dark exposure.
Authors: Huang Et al.
J Neurosci 2010;30:16636
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