DiMNF
Tocris Bioscience | Catalog # 4628
Key Product Details
Description
Product Description
DiMNF is a selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). Suppresses expression of CD55 and CD46 induced by IL-1β in an inflammatory tumor cell microenvironment; exhibits no effect on basal CD55 or CD46 expression.
Product Specifications for DiMNF
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 1.66 | 5 |
Preparing Stock Solutions for DiMNF
The following data is based on the product molecular weight 332.35.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.05 mM | 60.18 mL | 300.89 mL | 601.78 mL |
| 0.25 mM | 12.04 mL | 60.18 mL | 120.36 mL |
| 0.5 mM | 6.02 mL | 30.09 mL | 60.18 mL |
| 2.5 mM | 1.20 mL | 6.02 mL | 12.04 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Murray Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone. Mol.Pharmacol. 2011 PMID: 21127131
- Narayanan Selective aryl hydrocarbon receptor modulator-mediated repression of CD55 expression induced by cytokine exposure. J.Pharmacol.Exp.Ther. 2012 PMID: 22553215
- Labrecque Distinct roles for aryl hydrocarbon receptor nuclear translocator and Ah receptor in estrogen-mediated signaling in human cancer cell lines. PLoS ONE 2012 PMID: 22235307
Product Documents for DiMNF
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for DiMNF
For research use only
Related Research Areas
Customer Reviews for DiMNF (1)
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Assay Type: In VitroVerified Customer | Posted 08/20/2018Used this compound to test published results, had great success. Dissolved easily in DMSO
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