Chemical Name: 4-[(5,6-Dihydro[2,3'-bipyridin]-3(4H)-ylidene)methyl]-N,N-dimethylbenzenamine dihydrochloride
Biological ActivityPartial agonist at α7-containing neuronal nicotinic receptors and antagonist at α4β2 and other nicotinic receptors. Displays specific cognition-enhancing effects; improves long-term memory in rats.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors.
Kem et al.
Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21.
Arendash et al.
Brain Res., 1995;674:252
Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice.
Stevens et al.
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