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DMAB-anabaseine dihydrochloride

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DMAB-anabaseine dihydrochloride | CAS No. 154149-38-9 | Nicotinic (a7) Receptor Agonists
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Description: Partial agonist at α7 nAChR; also α4β2 antagonist

Chemical Name: 4-[(5,6-Dihydro[2,3'-bipyridin]-3(4H)-ylidene)methyl]-N,N-dimethylbenzenamine dihydrochloride

Purity: ≥98%

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Biological Activity

Partial agonist at α7-containing neuronal nicotinic receptors and antagonist at α4β2 and other nicotinic receptors. Displays specific cognition-enhancing effects; improves long-term memory in rats.

Technical Data

M.Wt:
364.32
Formula:
C19H21N3.2HCl
Solubility:
Soluble to 100 mM in water and to 25 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at -20°C
CAS No:
154149-38-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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VersaClone cDNA Plasmids

Human nAChR alpha 7/CHRNA7 (NP_000737) VersaClone cDNA

RDC0282

Human nAChR alpha 4/CHRNA4 (NP_000735) VersaClone cDNA

RDC0281

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