DTG

Tocris Bioscience | Catalog # 0841

High affinity ligand (σ1 = σ2)
Tocris Bioscience
Discontinued Product
0841 has been discontinued. View all General Sigma Receptor Ligands products.

Key Product Details

Description

High affinity ligand (σ1 = σ2)
View all General Sigma Receptor Ligands »

Product Description

Displays high and roughly equal affinity for both σ1 and σ2 receptors.

Product Specifications for DTG

Molecular Weight

239.32

Formula

C15H17N3

Storage

Store at RT

Chemical Name

1,3-Di-(2-tolyl)guanidine

CAS Number

97-39-2

PubChem ID

7333

InChI Key

OPNUROKCUBTKLF-UHFFFAOYSA-N

SMILES

CC1=C(NC(=N)NC2=C(C)C=CC=C2)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 5.98 25
Ethanol 5.98 25

Preparing Stock Solutions for DTG

The following data is based on the product molecular weight 239.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 16.71 mL 83.57 mL 167.14 mL
1.25 mM 3.34 mL 16.71 mL 33.43 mL
2.5 mM 1.67 mL 8.36 mL 16.71 mL
12.5 mM 0.33 mL 1.67 mL 3.34 mL

Calculators

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for DTG

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DTG

For research use only

Customer Reviews for DTG (1)

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  • DTG specifically protects sigma-1 and sigma-2 receptors binding sites.
    Name: Timur Mavlyutov
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: PC12
    Verified Customer | Posted 01/06/2018
    Photolabeling experiment by Iodoazidofenpropimorph labels multiple receptors, which can be later seen on auto radiogram. Sigma-1 (26kDa) and Sigma-2 (18kDa) receptors were also labeled. To be sure that these two bands are true Sigma-1 and Sigma-2 receptors, photolabeling experiment was performed in the presence of DTG (second lane). Both Sigma-1 and Sigma-2 receptors were selectively protected.
    DTG 0841

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