Chemical Name: 2-Phenyl-1,3-propanedioldicarbamate
Biological ActivityFelbamate is an anticonvulsant, acting as an antagonist at the NMDA-associated glycine binding site.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Felbamate antagonises isoniazid- and FG7142-induced reduction of GABAA receptor function in the mouse brain.
Serra et al.
Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings.
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felb. in DBA/2 mice.
De Sarro et al.
Selective antagonism of the anticonvulsant effects of felb. by glycine.
Coffin et al.
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