FPA 124

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FPA 124 | CAS No. 902779-59-3 | Akt (Protein Kinase B) Inhibitors
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Description: Akt/PKB inhibitor

Chemical Name: Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex

Product Details
Citations (1)
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Biological Activity

Akt/PKB inhibitor (IC50 = 100 nM) that interacts with the PH and kinase domains. Inhibits cell proliferation in various cancer cell lines in vitro and decreases NF-κB activity and tumor load in vivo.

Technical Data

M.Wt:
381.73
Formula:
C11H9Cl2CuN3O2S
Solubility:
Soluble to 10 mM in DMSO and to 10 mM in ethanol
Storage:
Store at +4°C
CAS No:
902779-59-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for FPA 124

The citations listed below are publications that use Tocris products. Selected citations for FPA 124 include:

1 Citation: Showing 1 - 1

  1. Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes.
    Authors: Liddell Et al.
    J Neuroinflammation  2016;13:49

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