FzM1.8

Catalog # Availability Size / Price Qty
6961/10
6961/50
FzM1.8 | CAS No. 2204290-85-5 | beta-Catenin Compounds
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Description: Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness

Chemical Name: 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid

Purity: ≥98%

Product Details
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Biological Activity

Frizzled 4 allosteric agonist (pEC50 = 6.4). Potentiates the β-catenin pathway in the absence of any WNT ligand, by biasing FZD4 signaling toward the FZD4/PI3K axis. Preserves stemness and promotes proliferation of undifferentiated cells.

Technical Data

M.Wt:
322.32
Formula:
C18H14N2O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2204290-85-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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