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Gap 26

  ( 3 citations )    
Product Datasheet
Catalog Number:1950
Chemical Name:
Product Details
Citations (3)
Reviews
Biological Activity
Peptide, corresponding to residues 63 - 75 of connexin 43, which is a gap junction blocker. Attenuates rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). Also inhibits IP3-induced ATP release, without inhibiting gap junctional coupling in endothelial cells.
Technical Data
  • M.Wt:
    1550.79
  • Formula:
    C70H107N19O19S
  • Sequence:
    VCYDKSFPISHVR
  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    197250-15-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Gap 26 include:

3 Citations: Showing 1 - 3
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  1. Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells.
    Authors: Thuringer Et al.
    BMC Vet Res  2015;6:10267
  2. Evidence for bystander signalling between human trophoblast cells and human embryonic stem cells.
    Authors: Jones Et al.
    Sci Rep  2015;5:11694
  3. Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo.
    Authors: Sakatani Et al.
    J Neurosci  2008;28:10928

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