Chemical Name: trans-4-[[4-[(6-Ethyl-2-benzothiazolyl)amino]-6-(phenylmethyl)-2-pyrimidinyl]amino]cyclohexanol
Biological ActivityGSK 2250665A is an Itk inhibitor (pKi = 9.2). Exhibits selectivity for Itk over Aurora B kinase and Btk (pIC50 values are 6.4 and 6.5, respectively) and a panel of other kinases. Inhibits IFNγ production in PBMCs.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Identification of a novel and selective series of Itk inhibitors via a template-hopping strategy.
Alder et al.
ACS Med.Chem.Lett., 2013;12:948
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for GSK 2250665A
There are currently no reviews for this product. Be the first to review GSK 2250665A and earn rewards!
Have you used GSK 2250665A?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image