Homoquinolinic acid

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptors subunits.
   Prado de Carvalho et al.
   Neurochem.Int., 1996;28:445
3. Structure/activity relations of NMDA receptor ligands as studied by their inhibition of [³H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes.
   Olverman et al.
   Neuroscience, 1988;26:17
4. Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones.
   Stone
   Br.J.Pharmacol., 1984;81:175

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