Chemical Name: N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide
Biological ActivityJNJ 1661010 is a selective, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 = 12 nM). Brain penetrant and active in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amid hydrolase.
Keith et al.
Citations for JNJ 1661010
The citations listed below are publications that use Tocris products. Selected citations for JNJ 1661010 include:
2 Citations: Showing 1 - 2
The cytoprotective effects of oleoylethanolamide in Ins-Secr.g cells do not require activation of GPR119.
Authors: Stone Et al.
Br J Pharmacol 2012;165:2758
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines.
Authors: Brown Et al.
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