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KM 11060

Catalog #: 3143
1 Citation Datasheet / COA / SDS

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3143 has been discontinued.
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KM 11060 | CAS No. 774549-97-2 | Other CFTR Compounds
1 Image
Description: Corrects F508del-CFTR trafficking

Chemical Name: 7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

KM 11060 is a corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

Technical Data

M.Wt:
422.33
Formula:
C19H17Cl2N3O2S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
774549-97-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for KM 11060

The citations listed below are publications that use Tocris products. Selected citations for KM 11060 include:

1 Citation: Showing 1 - 1

  1. Important role of platelets in modulating endotoxin-induced lung inflammation in CFTR-deficient mice.
    Authors: Zhao Et al.
    J Neuroinflammation  2013;8:e82683

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