Chemical Name: 7-Chloro-3-(cyclopropylcarbonyl)-4-hydroxy-2(1H)-quinolinone
Biological ActivityAn antagonist at the glycine-NMDA site (IC50 = 420 nM). Also a potent systemic anticonvulsant.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection.
3-Acyl-4-hydroxyquinolin-2(1H)-ones. Systemically active anticonvulsants acting by antagonism at the glycine site of the NMDA receptor complex.
Rowley et al.
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