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L-(-)-α-Methyldopa

Catalog #: 0584 Datasheet / COA / SDS

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0584 has been discontinued.
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L-(-)-α-Methyldopa | CAS No. 555-30-6 | Decarboxylase Inhibitors
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Description: Aromatic L-amino acid decarboxylase inhibitor

Chemical Name: 3-(3,4-Dihydroxyphenyl)-α-methyl-L-alanine

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Biological Activity

L-(-)-α-Methyldopa is a L-aromatic amino acid decarboxylase inhibitor. Antihypertensive.

Technical Data

M.Wt:
211.22
Formula:
C10H13NO4
Solubility:
Soluble to 75 mM in DMSO
Storage:
Store at RT
CAS No:
555-30-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Correlation between fall in blood pressure and in vivo amine release after α-methylDOPA.
    Kapoor and Chalmers
    Eur.J.Pharmacol., 1989;164:531
  3. The hypotensive activity and side effects of methyldopa, clonidine, and guanf.
    Van Zwieten et al.
    Hypertension, 1984;6:II-28

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