Catalog Number: 3225
Alternate Names: Des-Arg10-Kallidin
Biological Activity
Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin (Cat No. 3005).
Technical Data
  • M.Wt:
    1032.21
  • Formula:
    C50H73N13O11
  • Sequence:
    KRPPGFSPF
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    71800-36-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Classification of kinin receptors.
    Regoli et al.
    Biol.Chem., 2001;382:31
  2. Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins.
    Drapeau et al.
    J.Pharmacol.Exp.Ther., 1991;259:997
  3. International union of pharmacology. LV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences.
    Leeb-Lundberg et al.
    Pharmacol.Rev., 2005;57:27

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