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Lys-γ3-MSH

3611 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3611/1
Lys-γ3-MSH
1 Image
Description: Pro-opiomelanocortin (POMC) derived peptide
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Biological Activity

Lys-γ3-MSH is a pro-opiomelanocortin (POMC) derived peptide. Potentiates the steriodogenic action of corticotrophin on the adrenal cortex, possibly via the MC3 receptor. Potently stimulates lipolysis via activation of hormone-sensitive lipase (HSL).

Technical Data

M.Wt:
3018.27
Formula:
C128H193N45O39S
Sequence:
KYVMGHFRWDRFGRRNSSSSGSSGAGQ
Solubility:
Soluble to 1 mg/ml in 10% acetonitrile / water
Storage:
Store at -20°C
CAS No:
156159-18-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Evidence of a possible role fo Lys-γ3-MSH in the regulation of adipocyte function.
    Harmer et al.
    J.Endocrinol., 2008;196:149
  2. Lys-gamma3-MSH: a global regulator of hormone-sensitive lipase activity?
    Bicknell et al.
    Mol.Cell.Endocrinol., 2009;300:71
  3. The role of the melanocortin 3 receptor in mediating the effects of gamma-MSH peptides on the adrenal.
    Harmer and Bicknell
    Endocrine Res., 2004;30:629

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