Maprotiline hydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Maprotiline: A review of its pharmacological properties and therapeutic efficacy in mental depressive states.
   Pinder et al.
   Drugs, 1977;13:321
3. Biochemical and pharmacological tests for the prediction of ability of monoamine uptake blockers to inhibit the uptake of noradrenaline in-vivo: the effects of desipramine, maprotiline, femoxetine and cital.
   Pawlowski and Nowak
   J.Pharm.Pharmacol., 1987;39:1003
4. Behavioural effects in mice of subchronic chlordiazepoxide, maprot. and fluvox. II. The elevated plus-maze.
   Rodgers et al.
   Pharmacol.Biochem.Behav., 1997;57:127

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