Inhibitor of PARP-3 (IC50
= 0.89 μ
M). Displays selectivity for PARP-3 over PARP-1, PARP-2 and other ARDT enzymes (IC50
values are 6.3, 10.8 and >30 μ
M respectively). Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
Lindgren et al.
ACS Chem.Biol., 2013;8:1698