Chemical Name: (±)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
Biological ActivityMephenytoin is a CYP2C19 and CYP2B6 substrate. Anticonvulsant.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles.
Foti et al.
Drug Meta. Dispos., 2008;36:523
Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse events.
Tamminga et al.
Racemic and optically active hydantoins from disubstituted cyanoacetic acids.
Knabe and Wunn
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