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Catalog Number:3499
Chemical Name:4-Amino-5-chloro-2-methoxybenzoic acid 2-(1-piperidinyl)ethyl ester hydrochloride
Product Details
Supplemental Products
Reviews
Biological Activity
Potent 5-HT4 partial agonist (EC50 = 4 nM) that displays > 680-fold selectivity over 5-HT3 receptors (Ki values are 1.07 and 730 nM respectively). Increases sAPPα levels in the cortex in an animal model of Alzheimer's disease and exhibits progastrokinetic effects in vivo.
Potent 5-HT4 partial agonist (EC50 = 4 nM) that displays > 680-fold selectivity over 5-HT3 receptors (Ki values are 1.07 and 730 nM respectively). Increases sAPPα levels in the cortex in an animal model of Alzheimer's disease and exhibits progastrokinetic effects in vivo.
Technical Data
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M.Wt:349.25
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Formula:C15H21ClN2O3.HCl
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Solubility:Soluble to 50 mM in DMSO and to 20 mM in ethanol
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Purity:>99
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Storage:Desiccate at RT
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CAS No:186826-17-5
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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