Chemical Name: 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide
Biological ActivityML 161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). Thought to act allosterically. Also inhibits thrombin-induced platelet activation.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Complete Your Experiment
Discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the PAR1 receptor.
Dockendorff et al.
ACS Med.Chem.Lett., 2012;3:232
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for ML 161
There are currently no reviews for this product. Be the first to review ML 161 and earn rewards!
Have you used ML 161?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image