ML 161

Catalog # Availability Size / Price Qty
4570/10
4570/50
ML 161 | CAS No. 423735-93-7 | Protease-Activated Receptor Inhibitors
1 Image
Description: Inhibits PAR1-mediated platelet activation

Chemical Name: 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide

Purity: ≥98%

Product Details
Supplemental Products
Reviews

Biological Activity

ML 161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). Thought to act allosterically. Also inhibits thrombin-induced platelet activation.

Technical Data

M.Wt:
361.23
Formula:
C17H17BrN2O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
423735-93-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the PAR1 receptor.
    Dockendorff et al.
    ACS Med.Chem.Lett., 2012;3:232

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for ML 161

There are currently no reviews for this product. Be the first to review ML 161 and earn rewards!

Have you used ML 161?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.