MSPG

Discontinued Product

0854 has been discontinued.
View all Group II mGluR Antagonists products.
MSPG | CAS No. 169209-64-7 | Group II mGluR Antagonists
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Description: Group III and group II mGlu antagonist

Chemical Name: (RS)-α-Methyl-4-sulfonophenylglycine

Product Details
Citations (1)
Reviews

Biological Activity

MSPG is a relatively non-selective antagonist of presynaptic mGlu receptors in neonatal rat spinal cord and adult rat cerebrocortical mGlu receptors.

Technical Data

M.Wt:
245.25
Formula:
C9H11NO5S
Solubility:
Soluble to 100 mM in 1eq. NaOH
Storage:
Store at RT
CAS No:
169209-64-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors.
    Bedingfield et al.
    Eur.J.Pharmacol., 1996;309:71
  2. New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord.
    Jane et al.
    Neuropharmacology, 1995;34:851
  3. Antagonism of L-AP4- and (1S,3S)-ACPD-induced depression of dorsal root-evoked monosynaptic excitation of neonatal rat motoneurones by the novel antagonists MSPG and MPPG.
    Thomas et al.
    Br.J.Pharmacol., 1995;114:9P

Product Datasheets

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Citation for MSPG

The citations listed below are publications that use Tocris products. Selected citations for MSPG include:

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