MSPG
Chemical Name: (RS)-α-Methyl-4-sulfonophenylglycine
Biological Activity
MSPG is a relatively non-selective antagonist of presynaptic mGlu receptors in neonatal rat spinal cord and adult rat cerebrocortical mGlu receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors.
Bedingfield et al.
Eur.J.Pharmacol., 1996;309:71 -
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord.
Jane et al.
Neuropharmacology, 1995;34:851 -
Antagonism of L-AP4- and (1S,3S)-ACPD-induced depression of dorsal root-evoked monosynaptic excitation of neonatal rat motoneurones by the novel antagonists MSPG and MPPG.
Thomas et al.
Br.J.Pharmacol., 1995;114:9P
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Citation for MSPG
The citations listed below are publications that use Tocris products. Selected citations for MSPG include:
1 Citation: Showing 1 - 1
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Metabotropic glutamate receptors inhibit microglial glutamate release.
Authors: McMullan Et al.
ASN Neuro 2012;4
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