NCS-382

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice.
   King et al.
   J.Neural Transm., 1997;104:1177
3. A specific γ-hydroxybutyrate receptor ligand possesses both antagonist and anticonvulsant properties.
   Maitre et al.
   J.Pharmacol.Exp.Ther., 1990;255:657
4. Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist.
   Schmidt et al.
   Eur.J.Pharmacol., 1991;203:393

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