Catalog Number: 0780
Chemical Name: 6,7,8,9-Tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylideneacetic acid
Biological Activity
γ-Hydroxybutyric acid antagonist, anticonvulsant.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice.
    King et al.
    J.Neural Transm., 1997;104:1177
  2. Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist.
    Schmidt et al.
    Eur.J.Pharmacol., 1991;203:393
  3. A specific γ-hydroxybutyrate receptor ligand possesses both antagonist and anticonvulsant properties.
    Maitre et al.
    J.Pharmacol.Exp.Ther., 1990;255:657
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