Catalog Number: 0780
Chemical Name: 6,7,8,9-Tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylideneacetic acid
Biological Activity
γ-Hydroxybutyric acid antagonist, anticonvulsant.
Technical Data
  • M.Wt:
    218.25
  • Formula:
    C13H14O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Desiccate at +4°C
  • CAS No:
    520505-01-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice.
    King et al.
    J.Neural Transm., 1997;104:1177
  2. Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist.
    Schmidt et al.
    Eur.J.Pharmacol., 1991;203:393
  3. A specific γ-hydroxybutyrate receptor ligand possesses both antagonist and anticonvulsant properties.
    Maitre et al.
    J.Pharmacol.Exp.Ther., 1990;255:657

Have you used NCS-382?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

Feedback

Customer Information