(-)-Nicotine ditartrate

  ( 5 citations )    
Product Datasheet
Catalog Number:3546
Chemical Name:(S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-ditartrate salt
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Nicotinic acetylcholine receptor (nAChR) agonist (Ki values are 1, > 1000, 4000 and 7130 nM at α4β2, α1β1δγ, rat α7 and human α7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo.
Technical Data
  • M.Wt:
    462.41
  • Formula:
    C10H14N2.2C4H6O6
  • Solubility:
    Soluble to 100 mM in water and to 75 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    65-31-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (-)-Nicotine ditartrate include:

5 Citations: Showing 1 - 5
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  1. Spontaneous Release Regulates Synaptic Scaling in the Embryonic Spinal Network In Vivo
    Authors: Miguel Angel Garcia-Bereguiain Et al.
    The Journal of Neuroscience  2016;6:7268
  2. Identification and in vitro pharmacological characterization of a novel and selective α7 nicotinic acetylcholine receptor agonist, Br-IQ17B.
    Authors: Tang Et al.
    Iran Biomed J  2015;36:800
  3. Effect of Transient Inactivation of Ventral Tegmental Area on the Expression and Acquisition of Nicotine-Induced Conditioned Place Preference in Rats.
    Authors: Chalabi-Yani Et al.
    Elife  2015;19:214
  4. In vivo comparison of harmine efficacy against psychostimulants: preferential inhibition of the cocaine response through a glutamatergic mechanism.
    Authors: Owaisat Et al.
    Neurosci Lett  2012;525:12
  5. OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons.
    Authors: Leão Et al.
    Nat Neurosci  2012;15:1524

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