Catalog Number: 2521
Chemical Name: 5-Nitroso-8-quinolinol
Biological Activity
Histone deacetylase inhibitor. Causes cell differentiation and antiproliferative activity in MCF-7 human breast cancer cells in vitro and displays antitumor activity in vivo.
Technical Data
  • M.Wt:
    174.16
  • Formula:
    C9H6N2O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol
  • Storage:
    Store at RT
  • CAS No:
    3565-26-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model.
    Martirosyan et al.
    Biochem.Pharmacol., 2004;68:1729
  2. Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells.
    Martirosyan et al.
    J.Pharmacol.Exp.Ther., 2006;317:546

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