Chemical Name: N-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide
Biological ActivityEndogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC50 > 25 μM). However, potentiates TRPV1-mediated effects of NADA; lowers EC50 from ~ 90 to ~ 30 nM.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
N-OleoylDA, a novel endogenous capsaicin-like lipid that produces hyperalgesia.
Chu et al.
Actions of two naturally occurring saturated N-acylDAs on transient receptor potential vanilloid 1 (TRPV1) channels.
De Petrocellis et al.
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