Paprotrain

Catalog # Availability Size / Price Qty
4813/10
4813/50
Cat.No. 4813 - Paprotrain | C16H11N3 | CAS No. 57046-73-8
1 Image
Description: Reversible inhibitor of MKLP-2

Chemical Name: (Z)-α-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile

Product Details
Reviews

Biological Activity

Reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (Ki = 3.4 μM). Inhibits the basal ATPase activity of MKLP-2 (IC50 = 1.35 μM). Exhibits selectivity for MKLP-2 over 12 other members of the kinesin superfamily, including the closely-related MKLP-1. Cell permeable.

Technical Data

Formula:
C16H11N3
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
57046-73-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Paprotrain

There are currently no reviews for this product. Be the first to review Paprotrain and earn rewards!

Have you used Paprotrain?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.