Home / Formyl Peptide Receptor Antagonists / PBP 10

PBP 10

Catalog #: 4611
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4611/1
PBP 10
1 Image
Description: Selective FPR2 antagonist; cell permeable

Purity: ≥95%

Product Details
Citations (3)
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

PBP 10 is a selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.

Technical Data

M.Wt:
1712.1
Formula:
C84H126N24O15
Sequence:
QRLFQVKGRR

(Modifications: Gln-1 = Rhodamine-B-Gln)

Solubility:
Soluble to 2 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
794466-43-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

COA view current batch
Or select another batch:
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for PBP 10

The citations listed below are publications that use Tocris products. Selected citations for PBP 10 include:

3 Citations: Showing 1 - 3

  1. PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.
    Authors: Patel Et al.
    Nat Commun  2018;9:5390
  2. PLCζ Induced Ca2+ Oscillations in Mouse Eggs Involve a Positive Feedback Cycle of Ca2+ Induced InsP3 Formation From Cytoplasmic PIP2.
    Authors: Sanders
    Front. Cell Dev. Biol.  2018;6:36
  3. Antiviral activity of formyl peptide receptor 2 antagonists against influenza viruses.
    Authors: Courtin
    Antiviral Research  2017;143:252

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

VersaClone cDNA Plasmids

Human FPRL1/FPR2 (NP_001453) VersaClone cDNA

RDC0059

Mouse FPR2 (NP_032065) VersaClone cDNA

RDC0061

Reviews for PBP 10

There are currently no reviews for this product. Be the first to review PBP 10 and earn rewards!

Have you used PBP 10?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.