Catalog Number: 4611
Biological Activity
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Gln-1 = Rhodamine-B)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly.
    Cunningham et al.
    J.Biol.Chem., 2011;276:43390
  2. Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin.
    Forsman et al.
    J.Immunol., 2012;189:629
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