PBP 10

  ( 1 citations )    
Product Datasheet
Catalog Number:4611
Chemical Name:
Product Details
Citations (1)
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Biological Activity
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.
Technical Data
  • M.Wt:
    1712.1
  • Formula:
    C84H126N24O15
  • Sequence:
    QRLFQVKGRR

    (Modifications: Gln-1 = Rhodamine-B)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    794466-43-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for PBP 10 include:

1 Citations: Showing 1 - 1

  1. Antiviral activity of formyl peptide receptor 2 antagonists against influenza viruses.
    Authors: Courtin
    Antiviral Research  2017;143:252

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