Potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50
values are 280 pM and 16 nM respectively). Targets and labels β
-amyloid plaques in histochemical analysis.
Soluble to 50 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles.
Kacza et al.
A gorge-spanning, high-affinity cholinesterase inhibitor to explore β-amyloid plaques.
Elsinghorst et al.
The citations listed below are publications that use Tocris products. Selected citations for PE 154 include:
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