Chemical Name: 4-[[[7-(Diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid 2-(1,2,3,4-tetrahydro-9-acridinyl)hydrazide
Biological ActivityPE 154 is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50 values are 280 pM and 16 nM respectively). Targets and labels β-amyloid plaques in histochemical analysis.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles.
Kacza et al.
A gorge-spanning, high-affinity cholinesterase inhibitor to explore β-amyloid plaques.
Elsinghorst et al.
Citation for PE 154
The citations listed below are publications that use Tocris products. Selected citations for PE 154 include:
1 Citation: Showing 1 - 1
NE causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+.
Authors: Zemkova Et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for PE 154
There are currently no reviews for this product. Be the first to review PE 154 and earn rewards!
Have you used PE 154?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image