Home / IRAK Inhibitors / PF 06650833

PF 06650833

Catalog #: 6373 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6373/5
PF 06650833 | CAS No. 1817626-54-2 | IRAK Inhibitors
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Description: Potent and selective IRAK4 inhibitor

Chemical Name: 1-[[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxo-2-pyrrolidinyl]methoxy]-7-methoxy-6-isoquinolinecarboxamide

Purity: ≥98%

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Biological Activity

PF 06650833 is a potent and selective IRAK4 inhibitor (IC50 = 2 nM). Inhibits LPS-induced TNF-α secretion in vivo. Orally bioavailable.

Technical Data

M.Wt:
361.37
Formula:
C18H20FN3O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1817626-54-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

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