PKC 412

Catalog # Availability Size / Price Qty
2992/1
PKC 412 | CAS No. 120685-11-2 | Protein Kinase C Inhibitors
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Description: Protein kinase C inhibitor
Alternative Names: CGP 41251

Chemical Name: [9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide

Purity: ≥98%

Product Details
Citations (5)
Reviews

Biological Activity

Broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms (α, β, γ), PDFRβ, VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1, EGFR and MARK (microtubule affinity regulating kinase). Displays potent antitumor activity. Identified as targeting human host cell proteins that interact with SARS-CoV-2.

Technical Data

M.Wt:
570.64
Formula:
C35H30N4O4
Solubility:
Soluble to 15 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
120685-11-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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