pp60 c-src (521-533) (phosphorylated)

Name: pp60 c-src (521-533) (phosphorylated)
Brand: Tocris Bioscience
SKU: 1923

Tocris Bioscience | Catalog # 1923

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Product Documents

Inhibits tyrosine kinase activity of pp60c-src and pp60v-src

Discontinued Product

1923 has been discontinued. View all Src Family Kinase Inhibitors products.

Technical Data
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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

Inhibits tyrosine kinase activity of pp60c-src and pp60v-src

View all Src Family Kinase Inhibitors »

Product Description

pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60^c-src carboxy terminal regulatory domain; phosphorylated at Tyr⁵²⁷. Binds to pp60^c-src and pp60^v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.

Product Specifications for pp60 c-src (521-533) (phosphorylated)

Molecular Weight

1543.50

Formula

C₆₂H₉₅N₁₆O₂₈P

Storage

Store at -20°C

CAS Number

149299-77-4

PubChem ID

16137939

InChI Key

QTTDEIYNMOIHBO-VVTMTNTLSA-N

SMILES

[H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(OP(O)(O)=O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product.

Roussel Selective binding of activated pp60^c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60^c-src. Proc.Natl.Acad.Sci.U.S.A. 1991 PMID: 1720546
Harder Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. Biochem.J. 1994 PMID: 8135747

Product Documents for pp60 c-src (521-533) (phosphorylated)

Certificate of Analysis

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Product Specific Notices for pp60 c-src (521-533) (phosphorylated)

For research use only

Related Research Areas

Adhesion Molecules on Endothelial Cells

Intracellular Kinases

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