ProTx III

   
Product Datasheet
Catalog Number:5792
Chemical Name:
Product Details
Reviews
Biological Activity
Potent Nav1.7 blocker (IC50 = 2.5 nM). Also inhibits Nav1.1, Nav1.2, Nav1.3 and Nav1.6 in the nanomolar range. Exhibits no effects on Cav channels or nAChR at 5 μM. Demonstrates analgesic activity in vivo; antagonizes effects of scorpion-venom toxin OD1 at Nav1.7.
Technical Data
  • M.Wt:
    3802.41
  • Formula:
    C162H246N52O43S6
  • Sequence:
    DCLKFGWKCNPRNDKCCSGLKCGSNHNWCKLHI

    (Modifications: Disulfide bridge: 2-17, 9-22, 16-29, Ile-33 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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