PTAC oxalate

Catalog # Availability Size / Price Qty
4533/10
4533/50
Cat.No. 4533 - PTAC oxalate | C12H19N3S2.C2H2O4 | CAS No. 201939-40-4
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Description: Muscarinic receptor ligand; exhibits partial agonist and antagonist activity at different subtypes

Chemical Name: (1R,5R,6R)-6-[4-(Propylthio)-1,2,5-thiadiazol-3-yl]-1-azabicyclo[3.2.1]octane oxalate

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Muscarinic receptor ligand. Displays partial agonist activity at M2 and M4 receptors; exhibits antagonist effects at M1, M3 and M5 receptors (Ki values are 2.8, 0.2, 0.6, 0.2 and 0.8 nM respectively). Displays selectivity for muscarinic receptors over a range of neurotransmitter receptors and ion channels. Inhibits firing rate of dopaminergic cells in the limbic ventral tegmental area after acute administration, without binding to dopamine receptors.

Technical Data

M.Wt:
359.46
Formula:
C12H19N3S2.C2H2O4
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
201939-40-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for PTAC oxalate

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