PTAC oxalate

Discontinued Product

4533 has been discontinued.
View all Additional Non-selective Muscarinic Products products.
PTAC oxalate | CAS No. 201939-40-4 | Additional Non-selective Muscarinic Products
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Description: Muscarinic receptor ligand; exhibits partial agonist and antagonist activity at different subtypes

Chemical Name: (1R,5R,6R)-6-[4-(Propylthio)-1,2,5-thiadiazol-3-yl]-1-azabicyclo[3.2.1]octane oxalate

Purity: ≥98%

Product Details
Citations (1)

Biological Activity

PTAC oxalate is a muscarinic receptor ligand. Displays partial agonist activity at M2 and M4 receptors; exhibits antagonist effects at M1, M3 and M5 receptors (Ki values are 2.8, 0.2, 0.6, 0.2 and 0.8 nM respectively). Displays selectivity for muscarinic receptors over a range of neurotransmitter receptors and ion channels. Inhibits firing rate of dopaminergic cells in the limbic ventral tegmental area after acute administration, without binding to dopamine receptors.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for PTAC oxalate

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