Rac1 Inhibitor W56
Biological ActivityRac1 Inhibitor W56 is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1.
Control Peptide also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors.
Gao et al.
Citations for Rac1 Inhibitor W56
The citations listed below are publications that use Tocris products. Selected citations for Rac1 Inhibitor W56 include:
4 Citations: Showing 1 - 4
Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas.
Authors: Bessa Et al.
Cell Death Dis 2019;10:143
Co-targeting of Tiam1/Rac1 and Notch ameliorates chemoresistance against dox. in a biomimetic 3D lymphoma model.
Authors: Ikram Et al.
Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria.
Authors: Kruppa Et al.
Dev Cell 2018;44:484
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.
Authors: Zeineddine Et al.
Am J Physiol Lung Cell Mol Physiol 2015;10:57
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