Catalog Number: 2221
Biological Activity
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. Control peptide available (Cat. No. 2222).
Technical Data
  • M.Wt:
    1671.93
  • Formula:
    C74H117N19O23S
  • Sequence:
    MVDGKPVNLGLWDTAG
  • Solubility:
    Soluble to 2 mg/ml in PBS (pH 7.4)
  • Storage:
    Desiccate at -20°C
  • CAS No:
    1095179-01-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors.
    Gao et al.
    J.Biol.Chem., 2001;276:47530
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Rac1 Inhibitor W56 include:

1 Citations: Showing 1 - 1

  1. SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.
    Authors: Zeineddine Et al.
    Am J Physiol Lung Cell Mol Physiol 2015;10:57
Tocris Peptides
Description Application Cat# Citations Images  

Rac1 Inhibitor F56, control peptide

2222  
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