RBC8

Key Product Details

Product Description

RBC8 is a RalA and RalB GTPase inhibitor (EC₅₀ ~3.5 μM). Inhibits the binding of Ral to RaLBP1. Exhibits no detectable inhibition of Ras or RhoA activity. Suppresses growth of xenograft tumors in mice. Cell permeable.

Product Specifications for RBC8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for RBC8

The following data is based on the product molecular weight 424.45.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.36 mL	11.78 mL	23.56 mL
5 mM	0.47 mL	2.36 mL	4.71 mL
10 mM	0.24 mL	1.18 mL	2.36 mL
50 mM	0.05 mL	0.24 mL	0.47 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Yan Discovery and characterization of small molecules that target the GTPase Ral. Nature 2014 PMID: 25219851

Product Documents for RBC8