Biological Activity Selective protease-activated receptor-1 (PAR1) antagonist; displays no activity at PAR2, PAR3, or PAR4 subtypes. Blocks thrombin-induced platelet aggregation and activation of MAPK in HUVECs. Also inhibits angiogenesis in a chick embryo angiogenesis model in vivo.
Soluble to 25 mM in water and to 100 mM in DMSO
Store at -20°C
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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