SB 218795

Catalog # Availability Size / Price Qty
1376/10
1376/50
SB 218795 | CAS No. 174635-53-1 | NK3 Receptor Antagonists
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Description: Potent, selective non-peptide NK3 antagonist

Chemical Name: (R)-[[2-Phenyl-4-quinolinyl)carbonyl]amino]-methyl ester benzeneacetic acid

Purity: ≥99%

Product Details
Citations (4)
Supplemental Products
Reviews

Biological Activity

SB 218795 is a potent, selective and competitive non-peptide NK3 receptor antagonist (Ki = 13 nM at hNK3). Displays 90-fold and 7000-fold selectivity over hNK2 and hNK1 receptors respectively. Active in vivo, inhibiting agonist-induced pupillary constriction.

Technical Data

M.Wt:
396.44
Formula:
C25H20N2O3
Solubility:
Soluble to 100 mM in DMSO and to 5 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
174635-53-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license

Product Datasheets

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Citations for SB 218795

The citations listed below are publications that use Tocris products. Selected citations for SB 218795 include:

4 Citations: Showing 1 - 4

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