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Catalog Number:3527
Chemical Name:2,3-Dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-Indole-1-carboxamide dihydrochloride
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Selective 5-HT2C inverse agonist (pKb = 9.8). Displays selectivity over other 5-HT2 subtypes (pKi values are 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C respectively); also exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes. Displays anxiolytic activity in rat models.
Selective 5-HT2C inverse agonist (pKb = 9.8). Displays selectivity over other 5-HT2 subtypes (pKi values are 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C respectively); also exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes. Displays anxiolytic activity in rat models.
Technical Data
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M.Wt:501.33
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Formula:C22H19F3N4O2.2HCl
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Solubility:Soluble to 50 mM in DMSO
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Purity:>99
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Storage:Store at +4°C
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CAS No:200940-23-4
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:
The citations listed below are publications that use Tocris products. Selected citations for SB 243213 dihydrochloride include:
1 Citations: Showing 1 - 1
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