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SC 66

  ( 1 citations )    
Product Datasheet
Catalog Number:4398
Chemical Name:(2E,6E)-2,6-Bis(4-pyridinylmethylene)cyclohexanone
Product Details
Citations (1)
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Biological Activity
Allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. Exhibits anticancer activity in vitro and in vivo.
Technical Data
  • M.Wt:
    276.33
  • Formula:
    C18H16N2O
  • Solubility:
    Soluble to 75 mM in DMSO and to 75 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    871361-88-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SC 66 include:

1 Citations: Showing 1 - 1

  1. p22phox confers resistance to cisplatin, by blocking its entry into the nucleus.
    Authors: Hung Et al.
    J Cell Biol  2015;6:4110

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