-adrenoceptor and 5-HT1A/1B
receptor antagonist. pKB
values are 8.3 and 8.0 for 5-HT1A
receptors respectively. Centrally active following systemic administration in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
VII International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin).
Hoyer et al.
Evidence for the involvement of 5-HT1A receptors in the anticonflict effect of ipsapirone in rats.
Chojnacka-Wojcik and Przegalinski
Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites.
Engel et al.