SDZ 21009

Key Product Details

Product Description

SDZ 21009 is an β-adrenoceptor and 5-HT_1A/1B receptor antagonist. pK_B/pA₂ values are 8.3 and 8.0 for 5-HT_1A and 5-HT_1B receptors respectively. Centrally active following systemic administration in vivo.

Product Specifications for SDZ 21009

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SDZ 21009

The following data is based on the product molecular weight 348.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.87 mL	14.35 mL	28.70 mL
5 mM	0.57 mL	2.87 mL	5.74 mL
10 mM	0.29 mL	1.43 mL	2.87 mL
50 mM	0.06 mL	0.29 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Hoyer VII International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 1994 PMID: 7938165
• Engel Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT_1B binding sites. Naunyn-Schmied.Arch.Pharmacol.
• Chojnacka-Wojcik and Przegalinski Evidence for the involvement of 5-HT_1A receptors in the anticonflict effect of ipsapirone in rats. Neuropharmacology 1991 PMID: 1681448

Product Documents for SDZ 21009