Catalog Number: 1836
Alternate Names: MK 678
Biological Activity
Peptide agonist for sst2 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: > 1000 (sst1), 0.2 - 1.5 (sst2), 27 - 36 (sst3), > 127 (sst4), and 0.06 - 23 (sst5).
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Ala-1 = N-methyl-Ala, Trp-3 = D-Trp, Cyclized)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Molecular pharmacology of somatostatin receptors.
    Hoyer et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1994;350:441
  2. Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding to linear peptides.
    Raynor et al.
    Mol.Pharmacol., 1993;43:838
  3. Drug design at peptide receptors. Somatostatin receptor ligands.
    Hannon et al.
    J.Mol.Neurosci., 2002;18:15

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