SGS 518 oxalate
Chemical Name: 1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole 2,6-difluorobenzenesulfonic acid ester oxalate
Biological ActivitySGS 518 oxalate is a selective antagonist of the 5-HT6 subtype of the serotonin receptor. Useful for the treatment of cognitive impairment that is associated with schizophrenia and Alzheimer's disease.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
New serotonin 5-HT6 ligands from common feature pharmacophore hypotheses.
Kim et al.
Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways.
Romero et al.
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