SGS 518 oxalate

Key Product Details

Product Description

SGS 518 oxalate is a selective antagonist of the 5-HT₆ subtype of the serotonin receptor. Useful for the treatment of cognitive impairment that is associated with schizophrenia and Alzheimer's disease.

Product Specifications for SGS 518 oxalate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SGS 518 oxalate

The following data is based on the product molecular weight 510.51.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.96 mL	9.79 mL	19.59 mL
5 mM	0.39 mL	1.96 mL	3.92 mL
10 mM	0.20 mL	0.98 mL	1.96 mL
50 mM	0.04 mL	0.20 mL	0.39 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Romero Efficacy of selective 5-HT₆ receptor ligands determined by monitoring 5-HT₆ receptor-mediated cAMP signaling pathways. Br.J.Pharmocol. 2006 PMID: 16865095
• Kim New serotonin 5-HT₆ ligands from common feature pharmacophore hypotheses. J.Chem.Inf.Model. 2008 PMID: 18044950

Product Documents for SGS 518 oxalate