Basic fibroblast growth factor (bFGF) mimetic. Mimics the neuroprotective effects of bFGF; prevents glutamate-induced neuronal death. Increases levels of CALB1 gene expression in cerebrocortical neurons. Triggers phosphorylation of FGFR, ERK1 and ERK2.
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SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.
Murayama et al.
ACS Chem.Neurosci., 2013;4:266