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T 26c disodium salt

Catalog #: 6134 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6134/5
6134/25
T 26c disodium salt | CAS No. 869298-22-6 | Synthetic Metalloprotease Inhibitors
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Description: Highly potent and selective MMP13 inhibitor

Chemical Name: Disodium 4-[[[[2-[[[[3-(Methyloxy)phenyl]methyl]amino]carbonyl]-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl]methyl]oxy]methyl]benzoate

Purity: ≥98%

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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

T 26c disodium salt is a highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits >2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable.

Technical Data

M.Wt:
523.47
Formula:
C24H19N3Na2O6S
Solubility:
Soluble to 10 mM in DMSO with gentle warming and to 1 mM in water
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
869298-22-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the T-26c probe summary on the SGC website.

Product Datasheets

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