Chemical Name: 1,2,3,4-Tetrahydro-5-aminoacridine hydrochloride
Biological ActivityPotent cholinesterase inhibitor, a cognition enhancer in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Tacrine: a pharmacological review.
Freeman and Dawson
Tetrahydro-9-aminoacridine has mixed actions on muscarinic currents and blocks opioid currents in rat locus ceruleus neurons.
Osborne and Christie
A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066.
Snape et al.
THA- A review of the literature and its use in treatment of five overdose patients.
Summers and Kaufman
Citation for Tacrine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Tacrine hydrochloride include:
1 Citation: Showing 1 - 1
M3 muscarinic acetylcholine receptor expression confers differential cholinergic modulation to neurochemically distinct hippocampal basket cell subtypes.
Authors: Rio Et al.
Mol Cell Endocrinol 2010;30:6011
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