Chemical Name: 1-(3,4,5-Trihydroxyphenyl)-1-nonanone
Biological ActivityNur77 agonist. Binds Nur77 and promotes translocation of the receptor to the mitochondria resulting in autophagy in melanoma cell lines.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Wang et al.
Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Li et al.
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